Reviews and Book Chapter/ Other Invited Chapters (bottom of the page)

Research Publication


131. Generation and trapping of electron-deficient 1,2-cyclohexadienes. Unexpected hetero-Diels-Alder reactivity. Wang B, Constantin MG, Singh S, Zhou Y, Davis RL, West FG, Org Biomol Chem 2021, 19, 399-405.

130. Enhancing the activity of platinum-based drugs by improved inhibitors of ERCC1-XPF-mediated DNA repair. Ciniero G, Elmenoufy AH, Gentile F, Weinfeld M, Deriu MA, West FG, Tuszynski JA, Dumontet C, Cros-Perrial E, Jordheim LP. Cancer Chemother Pharmacol 2021, 87, 259-267.


129. Pharmacological targets and emerging treatments for respiratory syncytial virus bronchiolitis. Elawar F, Oraby AK, Kieser Q, Jensen LD, Culp T, West FG, Marchant DJ, Pharmacol Ther 2020, 107712


128. A Mild Method for the Generation and Interception of 1,2-Cycloheptadienes with 1,3-Dipoles. Almehmadi YA, West FG,  Org Lett 2020, 22, 6091-6095.

127. Design, synthesis and in vitro cell-free/cell-based biological evaluations of novel ERCC1-XPF inhibitors targeting DNA repair pathway. Elmenoufy AH, Gentile F, Jay D, Karimi-Busheri F, Yang X, Soueidan OM, Mani RS, Ciniero G, Tuszynski JA, Weinfeld M, West FG, Eur J Med Chem 2020, 204, 112658.

126. Computer-aided drug design of small molecule inhibitors of the ERCC1-XPF protein-protein interaction. Gentile F, Elmenoufy AH, Ciniero G, Jay D, Karimi-Busheri F, Barakat KH, Weinfeld M, West FG, Tuszynski JA, Chem Biol Drug Des 2020, 95, 460-471.


125. Targeting DNA Repair in Tumor Cells via Inhibition of ERCC1-XPF. Elmenoufy AH, Gentile F, Jay D, Karimi-Busheri F, Yang X, Soueidan OM, Weilbeer C, Mani RS, Barakat KH, Tuszynski JA, Weinfeld M, West FG, J Med Chem 2019, 62, 7684-7696.

124. Strain-Activated Diels–Alder Trapping of 1,2-Cyclohexadienes: Intramolecular Capture by Pendent Furans. Lofstrand VA, McIntosh KC, Almehmadi YA, West FG, Org Lett 2019, 21, 6231-6234.


123. Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. Ganesan A, Ahmed M, Okoye I, Arutyunova E, Babu D, Turnbull WL, Kundu JK, Shields J, Agopsowicz KC, Xu L, Tabana Y, Srivastava N, Zhang G, Moon TC, Belovodskiy A, Hena M, Kandadai AS, Hosseini SN, Hitt M, Walker J, Smylie M, West FG, Siraki AG, Lemieux MJ, Elahi S, Nieman JA, Tyrrell DL, Houghton M, Barakat K., Sci Rep 2019, 9, 12392.



122. The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C. Li MX, Gelozia S, Danmaliki GI, Wen Y, Liu PB, Lemieux MJ, West FG, Sykes BD, Hwang PM, Biochem Biophys Rep 2018, 16, 145-151.

121. Molecular Imaging of GLUT1 and GLUT5 in Breast Cancer: A Multitracer Positron Emission Tomography Imaging Study in Mice. Wuest M, Hamann I, Bouvet V, Glubrecht D, Marshall A, Trayner B, Soueidan OM, Krys D, Wagner M, Cheeseman C, West F, Wuest F, Mol Pharmacol 2018, 93, 79-89.


120. Dual Catalytic Synthesis of Antiviral Compounds Based on Metallocarbene–Azide Cascade Chemistry. Bren Jordan P. Atienza, Lionel D. Jensen, Sarah L. Noton, Anil Kumar Victoria Ansalem, Tom Hobman, Rachel Fearns, David J. Marchant, and F. G. West, JOC 2018, 83, 6829-6842


119. One‐Pot Generation of Bicyclo [3.1. 0] hexanols and Cyclohexanones by Double Interrupted Nazarov Reactions. S. Gelozia, Y. Kwon, R. McDonald, F. G. West, Chem. Eur. J. 201824, 6052


118. Evidence for heterolytic cleavage of a cyclic oxonium ylide: implications for the mechanism of the Stevens [1,2]-shift. Seyedeh Nargess Hosseini , Jeffrey R. Johnston, Frederick G. West. Chem. Commun. 201753, 12654-12656. (pdf)

117. Intercepting the Nazarov Oxyallyl Intermediate with α-Formylvinyl Anion Equivalents to Access Formal Morita–Baylis–Hillman Alkylation Products. Yen-Ku Wu, Rongrong Lin, Frederick G. West Synlett 2017, 28, 1486-1490. (pdf)

116. Tunable GLUT–Hexose Binding and Transport via Modulation of Hexose C‐3 Hydrogen‐Bonding Capabilities. Venkata Pavan Kumar Kondapi, Olivier‐Mohamad Soueidan, Christopher I. Cheeseman, Frederick G. West Chemistry-A European Journal 2017, 23, 8073-8081. (pdf)

115. Oxidation‐Initiated Cyclizations of Pentadienyl Ethers: An Alternative Entry to the Nazarov Reaction. Ryan J. Fradette, Minkyu Kang, Frederick G. West Angewandte Chemie International Edition 2017, 56, 6335-6338. (pdf)

114. Synthesis and biological evaluation of structurally simplified noscapine analogues as microtubule binding agents. Peter E. Ghaly, Cassandra D.M. Churchill, Rabab M. Abou El-Magd, Zuzana Hájková, Pavel Dráber, Frederick G. West, Jack A. Tuszynski Canadian Journal of Chemistry, 2017, 95, 649-655. (pdf)

113. Fluorescent Hexose Conjugates Establish Stringent Stereochemical Requirement by GLUT5 for Recognition and Transport of Monosaccharides. Olivier-Mohamad Soueidan, Thomas W. Scully, Jatinder Kaur, Rashmi Panigrahi, Alexandr Belovodskiy, Victor Do, Carson D. Matier, M. Joanne Lemieux, Frank Wuest, Chris Cheeseman, Frederick G. West ACS Chemical Biology 2017, 12, 1087-1094. (pdf)

112. Medium-Sized Cyclic Ethers via Stevens [1, 2]-Shift of Mixed Monothioacetal-Derived Sulfonium Ylides: Application to Formal Synthesis of (+)-Laurencin. Rongrong Lin, Liya Cao, Frederick G. West Organic letters 2017, 19, 552-555. (pdf)


111. Structures reveal details of small molecule binding to cardiac troponin. Fangze Cai, Monica X. Li, Sandra E. Pineda-Sanabria, Shorena Gelozia, Steffen Lindert, Frederick G. West, Brian D. Sykes, Peter M. Hwang Journal of molecular and cellular cardiology 2016,101, 134-144. (pdf)

110. Interrupting the Nazarov Cyclization with Bromine. Devon J. Schatz, Yonghoon Kwon, Thomas W. Scully, Frederick G. West J. Org. Chem. 2016, 81, 12494-12498. (pdf)

109. A new antiproliferative noscapine analogue: chemical synthesis and biological evaluation. Peter E. Ghaly, Rabab M. Abou El-Magd, Cassandra D. M. Churchill, Jack A. Tuszynski, F. G. West  Oncotarget 2016, 7, 40518-40530. (pdf)

108. Efficient Trapping of 1,2-Cyclohexadienes With 1,3-Dipoles. Verner A. Lofstrand, F. G.West Chem. Eur. J. 2016, 22, 10763-10767. (pdf)

107. Efficient and Easy Access to Optically Pure Tetrasubstituted Tetrahydrofurans via Stereoselective Opening of C2-Symmetric Epoxide and Aziridine Rings. Venkata Pavan Kumar Kondapi, Olivier-Mohamad Soueidan, Seyedeh Nargess Hosseini, Nauras Jabari, and Frederick G. West. Eur. J. Org. Chem. 2016, 1367–1379 (pdf)


106. 1,4-diketones from Cross-conjugated Dienones: Potassium Permanganate -Interrupted Nazarov Reaction. Yonghoon Kwon, Devon J. Schatz, and Prof. Frederick G. West. Angewantdte Chemie International Edition. 2015, 54, 9940-9943 (pdf) 

105. New fluorinated fructose analogs as selective probes of the hexose transporter protein GLUT5. Olivier-Mohamad Soueidan, Brendan J. Tryaner, Tina N. Grant, Jeff, R. Henderson, Frank Wuest, F.G. West and Chris I. Cheeseman.  Org. Biomol. Chem., 2015, 13, 6511-6521 (pdf)

104. Reactivity and Stereoselectivity of 6π and Nazarov Electrocyclizations of Bridged Bicyclic Trienes and Divinyl Ketones. Ashay Patel, F. G. West, and K. N. Houk. J. Org. Chem., 2015, 80 (5), pp 2790–2795 (pdf)

103. Diastereoselective N-quaternization of piperidines. Christine R. Dunbar, F.G. West. Can. J. Chem. 2015, 93(4): 468-476 (pdf)


102. “Experimental and Computational Studies on Interrupted Nazarov Reactions: Exploration of Umpolung Reactivity at the α-Carbon of Cyclopentanones,” Yen-Ku Wu, Christine R. Dunbar,Robert McDonald, Michael J. Ferguson and F. G. West, J. Am. Chem. Soc. 2014, 136, pp 14903-14911 (pdf)

102. “Experimental and Computational Studies on Interrupted Nazarov Reactions: Exploration of Umpolung Reactivity at the α-Carbon of Cyclopentanones,” Yen-Ku Wu, Christine R. Dunbar,Robert McDonald, Michael J. Ferguson and F. G. West, J. Am. Chem. Soc. 2014, 136, pp 14903-14911 (pdf)

101. “Azide trapping of metallocarbenes: generation of reactive C-acylimines and domino trapping with nucleophile,” Tina M. Bott, Bren Jordan Atienza and F. G. West, RSC Adv., 2014, 4, 31955–31959 (pdf)

100. “Automated synthesis and dosimetry of 6-deoxy-6-[18F]fluoro-D-fructose (6-[18F]FDF): a radiotracer for imaging of GLUT5 in breast cancer ,“ Vincent Bouvet, Hans S Jans, Melinda Wuest, Olivier-Mohamad Soueidan, John Mercer, Alexander JB McEwan, Frederick G West, Chris I Cheeseman, Frank Wuest, Am. J. Nucl. Med. Mol. Imaging 2014, 4, 248259 (pdf)

99. Formal Homologous Aldol Reactions: Interrupting the Nazarov Cyclization via Carboalkoxylation of Alkynes,” Yen-Ku Wu and F. G. West, Org. Lett. 2014, 16, 2534–2537 (pdf)

98. “α-Hydroxycyclopentanones via one-pot oxidation of the trimethylaluminum-mediated Nazarov reaction with Triplet Oxygen,” Yonghoon Kwon, Owen Scadeng, Robert McDonald, F. G. West, Chem. Commun., 2014, 50, 5558-5560. (pdf)

97.Ready Access to Alkylidenecyclopentenones by Nazarov Cyclization/β-Elimination of 2-Hydroxyalkyl-1,4-dien-3-ones,” Owen Scadeng, F. G. West, Eur. J. Org. Chem. 2014, 1860-1865. (pdf)

96.Efficient synthesis of bicyclo[6.3.0]undecadienes by Nazarov cyclization/regioselective elimination,” Carson D. Matier, Yonghoon Kwon, F. G. West, Can. J. Chem. 2014, 92. 58-61. (pdf)


95.“Hydroxylic additives enhance yield and scalability of silicon-directed Nazarov reaction,” Shaon     Joy, Waka Nakanishi, F. G. West, Tetrahedron Lett. 2013, 54, 5573-5576. (pdf)


  1. 94.“Organoaluminum-Mediated Interrupted Nazarov Reaction,” Yonghoon Kwon, Robert McDonald, F. G. West, Angew. Chem. Int. Ed. 2013, 52, 8616-8619.  (pdf) 

93.“Nazarov Reactions of Vinyl Cyclopropylamines: An Approach to the Imino-Nazarov Problem,”   Sara A. Bonderoff , Tina N. Grant , F. G. West *, and Martin Tremblay, Org. Lett. 2013, 15, 2888-2891. (pdf)


92.“Regioselective Synthesis of 2-Iminooxazinones from Dioxinones and Carbodiimides,” Jeffrey R. Johnston, F. G. West, Tetrahedron Lett. 2012, 53, 5479-5482. (pdf)

91.“Construction of α-Amido-indanones via Formal Allenamide Hydroacylation/Nazarov Cyclization,” Yen-Ku Wu, Tianmin Niu, F. G. West, Chem. Commun. 2012, 48, 9186-9188. (pdf)

90.“Prion Inhibition with Multivalent PrPSc Binding Compounds,” Charles E. Mays, Shaon Joy, Lei Li, Linghui Yu, Sacha Genovesi, Frederick G. West, David Westaway, Biomaterials 2012, 33, 6808-6822. (pdf)

89.“Superacid Catalyzed Friedel-Crafts Cyclization of Unactivated Alkenes,” Sara A. Bonderoff, F. G. West, Martin Tremblay, Tetrahedron Lett. 2012, 53, 4600-4603. (pdf)


88.“Homologous Mukaiyama Reactions via Trapping of the Nazarov Intermediate with Silyloxyalkenes,” Yen-Ku Wu, Robert McDonald, F. G. West, Org. Lett. 2011, 13, 3584-3587. (pdf)


87.“Radiopharmacological Evaluation of 6-Deoxy-6-[18F]fluoro-d-fructose as a Radiotracer for PET Imaging of GLUT5 in Breast Cancer,” Melinda Wuest, Brendan J. Trayner, Tina N. Grant, Hans-Soenke Jans, John R. Mercer, David Murray, Frederick G. West, Alexander J. B. McEwan, Frank Wuest, Chris I. Cheeseman, Nucl. Med. Biol. 2011, 38, 461-475. (pdf)

86.“Expedient Route to the Tigliane-Daphnane Skeleton via Oxonium Ylide [1,2]-Shift,” Craig Stewart, Robert McDonald, F. G. West, Org. Lett. 2011, 13, 720-723. (pdf) 

85.“Intermolecular [3+3]-Cycloadditions of Azides with the Nazarov Intermediate,” Owen Scadeng, Michael J. Ferguson, F. G. West, Org. Lett. 2011, 13, 114-117. (pdf)

84.“Olefination of α,α′-Divinyl Ketones through Catalytic Meyer−Schuster Rearrangement,” Curtis J. Rieder, Karl J. Winberg, F. G. West, J. Org. Chem. 2011, 76, 50-56. (pdf)


83.“Brønsted Acid-Mediated Nazarov Cyclization of Vinylallenes,” Yen-Ku Wu, F. G. West, J. Org. Chem. 2010, 75, 5410-5413. (pdf)

82.“Heteroaromatic Trapping of Tricyclic 2-Oxidocyclopentenyl Cations: A Surprisingly Efficient Example of Intermolecular Interrupted Nazarov Reaction,” Curtis J. Rieder, Ryan J. Fradette, F. G. West, Heterocycles 2010, 80, 1413-1427. (pdf)


81.“Fluorinated Fructose Derivatives for PET Imaging,” Brendan J. Traner, Tina N. Grant, F. G. West, Chris I. Cheeseman, Bioorg. Med. Chem. 2009, 17, 5488-5495. (pdf)

80.“Cyclization of Cross-Conjugated Trienes: The Vinylogous Nazarov Reaction,” Curtis J. Rieder, Karl J. Winberg, F. G. West, J. Am. Chem. Soc. 2009, 131, 7504-7505. (pdf)

79.“Fused Ring Systems Derived from Reactions of Half-Open Titanocenes with Diynes:  Syntheses, Characterization, Cage Rearrangements, and Structural Studies,” Anne M. Wilson, Arnold L. Rheingold, Thomas E. Waldman, Michael Klein, Frederick G. West, Richard D. Ernst, J. Organometal. Chem. 2009,694, 1112-1121. (pdf)

78.“One-Step Ring Expansion of Azetidines via Ammonium Ylide [1,2]-Shifts: A Simple Route to Substituted Pyrrolidines,” Tina M. Bott, John A. Vanecko, F. G. West, J. Org. Chem. 2009, 74, 2832-2836.(pdf)

77.“Diastereocontrol in [4+4]-photocycloadditions of pyran-2-ones: effect of ring substituents and chiral ketal,” Lei Li, John A. Bender, F. G. West, Tetrahedron Lett.2009, 50, 1188-1192. (pdf)


76.“Ring Expansion of Lactones and Lactams via Propiolate 1-Carbon Intercalation,” Tina N. Grant, Chantel L. Benson, F. G. West, Org. Lett.  2008, 10, 3895-3988. (pdf)

75.“Concise Route to Triquinanes from Pyran-2-ones,” Lei Li, Robert McDonald, F. G. West, Org. Lett.  2008, 10, 3733-3736. (pdf)

74.“Cyclooctatrienes from Pyran-2-ones via a Tandem [4+4]-Photocycloaddition/Decarboxylation Process,” Lei Li, Charles E. Chase, F. G. West, Chem. Commun. 2008, 4025-4027. (pdf)

73.“Construction of aryl-substituted triquinanes through the interrupted Nazarov reaction,” Curtis J. Rieder, Ryan J. Fradette, F. G. West, Chem. Commun.  2008, 1572-1574. (pdf)


72.“Domino Electrocyclization/Azide-Capture/Schmidt Rearrangement of Dienones: One-Step Synthesis of Dihydropyridones from Simple Building Blocks,” Song, D., Rostami, A., West, F. G., J. Am. Chem. Soc.2007, 129, 12019-12022.  (pdf)

71.“Interrupted Nazarov Reactions Using Dichlorocyclopropanes: A Novel Mode of Arene Trapping,” Grant, T. N., West, F. G. Org. Lett. 2007, 9, 3789-3792. (pdf)

70.“Efficient intermolecular [3+2] trapping of the Nazarov intermediate with vinyl sulfides,” Mahmoud, Bahja; West, F. G. Tetrahedron Lett.  2007, 48, 5091-5094. (pdf)

69.“Highly Stereoselective 6π Electrocyclization of Bridged Bicyclic 1,3,5-Trienes,” Benson, C. L.; West, F. G. Org. Lett. 2007, 9, 2545-2548.  (pdf)

68.“Intramolecular Azide Trapping of the Nazarov Intermediate: Formation of Peroxy-Bridged Indolizidinones via a Deep-Seated Rearrangement and Aerobic Oxidation,” Rostami, A.; Wang, Y.; Arif, A. M.; McDonald, R.; West, F. G. Org. Lett. 2007, 9, 703-706. (pdf)


67.“Construction of fused bis(pyran) units from enones via a hydrosilylation dihydroxylation-acetalization-reduction sequence,” Liu, Xuan; West, F. G., Chem. Commun. 2006, 5036-5038. (pdf)

66.“[1,2]- or [2,3]-Rearrangement of Onium Ylides of Allyl and Benzyl Ethers and Sulfides via In Situ-generated Iodonium Ylides,” Graham K. Murphy and F. G. West, Org. Lett. 2006, 8, 4359-4361. (pdf)

65.“Facial Diastereoselectivity In [4+4]-Photocycloadditions of Pyran-2-ones: Surprising Effect of an Adjacent Chiral Center,” Dong Song, Robert McDonald and F. G. West, Org. Lett. 2006, 8, 4075- 4078. (pdf)

64.“A New Approach to the Nazarov Reaction via Sequential Electrocyclic Ring Opening and Ring Closure,” Tina N. Grant and F. G. West, J. Am. Chem. Soc. 2006, 128, 9348–9349. (pdf)

63.“Polycyclic Oxonium Ylides:  Use of Cyclic Acetals as Convenient Scaffolds in the Construction of Fused Bicyclic Compounds Containing a Medium Ring,” Graham K. Murphy, Fredrik P. Marmsäter, F. G. West, Can. J. Chem. 2006, 84, 1470-1486. (pdf)


62.“Halide Trapping of the Nazarov Intermediate in Strained Polycyclic Systems:  A New Interrupted Nazarov Reaction,” Timoghy D. White, F. G. West, Tetrahedron Lett. 2005, 46, 5629–5632. (pdf)

61.“Unexpected Participation of an Unconjugated Olefin During Nazarov Cyclization of Bridged Bicyclic Dienones,” Sören Giese, Robert D. Mazzola, Jr., Clare M. Amann, Atta M. Arif, F. G. West, Angew. Chem.Int. Ed. 2005, 44, 6546–6549. (pdf)

60.“Ring Expansion of Azetidinium Ylides:  Rapid Access to the Pyrrolizidine Alkaloids Turneforcidine and Platynecine,” John A. Vanecko, F. G. West, Org. Lett. 2005, 7, 2949–2952. (pdf)

59.“Stereoselective Nazarov Cyclizations of Bridged Bicyclic Dienones,” Robert D. Mazzola, Jr., Timothy D. White, Heidi R. Vollmer-Snarr, F. G. West, Org. Lett. 2005, 7, 2799–2801. (pdf)

58.“Hydrazulene Ring Systems via Heteroatom-Assisted [1,2]-Shift of Oxonium and Sulfonium Ylides,” Graham K. Murphy and F. G. West, Org. Lett. 2005, 7, 1801-1804. (pdf)


57.“Convenient Route to Centro-Substituted Triquinacene Skeletons via the Interrupted Nazarov Reaction,” Ashantai Yungai and F. G. West, Tetrahedron Lett. 2004, 45, 5445-5448. (pdf)

56.“Catalyst and Ring Size Effects on Periselectivity of Oxonium Ylide Rearrangements,” Fredrik P. Marmsäter, John A. Vanecko and F. G. West, Org. Lett. 2004, 6, 1657-1660. (pdf)

55.“Improved Yields with Added Copper(I) Salts in Carbonylative Stille Couplings of Sterically Hindered 1-Substituted Vinylstannanes,” Robert D. Mazzola, Jr., Sören Giese, Chantel L. Benson and F. G. West, J. Org. Chem. 2004, 69, 220-223. (pdf)

54.“Efficient Construction of Benzohydrindenones from Aryltrienones via Domino Nazarov Electrocyclization/Electrophilic Aromatic Substitution,” Cindy C. Browder, Fredrik P. Marmsäter and F. G. West, Can. J. Chem. 2004, 82, 375-385. (pdf)


53.“Cyclooctanoid Ring Systems from Mixed Acetals via Heteroatom-Assisted [1,2]-Shift of Oxonium Ylides,” Fredrik P. Marmsäter, Graham K. Murphy and F. G. West, J. Am. Chem. Soc. 2003, 125, 14724-14725. (pdf)

52.“A Formal Intermolecular 4+4 Approach to Cyclooctanoids:  4+3 Capture of the Nazarov Oxyallyl Intermediate with Simple 1,3-Dienes,” Yong Wang, Brenden Schill and F. G. West, Org. Lett. 2003, 5, 2747-2750. (pdf)

51.“Stereoselective Formation and Rearrangement of Morpholinium Ylides Derived from Copper Carbenoids,” Kevin W. Glaeske, B. N. Naidu and F. G. West, Tetrahedron: Asymmetry 2003, 14, 917-920. (pdf)


50.“A Novel, Stereoselective Silyl-Directed Stevens [1,2]-Shift of Ammonium Ylides,” John A. Vanecko and F. G. West, Org. Lett. 2002, 4, 2813-2816. (pdf)

49.“Cyclic Oxonium Ylides:  Building Blocks for Iterative Synthesis of Polycyclic Ethers,” Fredrik P. Marmsäter, John A. Vanecko and F. G. West, Tetrahedron 2002, 58, 2027-2040. (pdf)

48.“A Convenient Method for the Synthesis of Terminal (E)-1,3-Dienes,” Yong Wang and F. G. West, Synthesis 2002, 99-103. (pdf)

47.“Equilibrium and Kinetic Analysis of the Interactions Between Vitamin B12 Binding Proteins and Cobalamins by Surface Plasmon Resonance,” Michelle J. Cannon, David G. Myszka, Joshua D. Bagnato, David H. Alpers, Frederick G. West and Charles B. Grissom, Analytical Biochemistry 2002, 305, 1-9. (pdf)


46.“Highly Efficient Trapping of the Nazarov Intermediate with Substituted Arenes,” Cindy C. Browder, Fredrik P. Marmsäter and F. G. West, Org. Lett. 2001, 3, 3033-3035. (pdf)

45.“Iterative Approach to Polycyclic Ethers based on Stereoselective Oxonium Ylide [2,3]-Shifts,” Fredrik P. Marmsäter and F. G. West, J. Am. Chem. Soc. 2001, 123, 5144-5145. (pdf)

44.“Solvent Trapping of 4-Pyrone-Derived Oxyallyls. A Novel Cyclopentannulation Method,” Mike Fleming, Peter V. Fisher, Gamini U. Gunawardena, Yinghua Jin, Chen Zhang, Wei Zhang, Atta M. Arif and F. G. West, Synthesis, 2001, 1268-1274.

43.“Synthesis and Characterization of Fluorescent Cobalamin (CobalaFluor) Derivatives for Imaging,” Claudia Smeltzer, Michelle J. Cannon, Patrick Pinson, John S. Munger, F. G. West and Charles B. Grissom, Org. Lett. 2001, 3, 799-801. (pdf)

42.“10-Deacetylbaccatin III Dimethyl Sulfoxide Disolvate,” James K. Harper, N. Kent Dalley, Anna E. Mulgrew, F. G. West and David M. Grant,  Acta Crystallogr., Sect. C:  Cryst. Struct. Commun. 2001, C57(1), 64-65.


41.“Coumarin Derivatives and Breast-Feeding,” Steven L. Clark, T. Flint Porter and Frederick G. West, Obstet. Gynecol. 2000, 95, 938-940. (pdf)

40.“Ionic Hydrogenation of Oxyallyl Intermediates:  The Reductive Nazarov Cyclization,” Soren Giese and F. G. West, Tetrahedron 2000, 56, 10221-10228. (pdf)

39.“Synthesis, Characterization, and Organic Chemistry of an Edge-Bridged Half-Open Titanocene,” Anne M. Wilson, F. G. West, Arnold L. Rheingold and Richard D. Ernst, Inorg. Chim. Acta 2000, 300/302, 65-72. (pdf)

38.“Intermolecular Trapping of the Nazarov Intermediate:  Domino Electrocyclization/[3+2] Cycloadditions with Allylsilanes,” Sören Giese, Lars Kastrup, Dirk Stiens and F. G. West, Angew. Chem. Int. Ed. Engl.2000, 39, 1970-1973. (pdf)


37.“Nazarov Initiated Diastereoselective Cascade Polycyclization of Aryltrienones,” John A. Bender, Atta M. Arif and F. G. West, J. Am. Chem. Soc. 1999, 121, 7443-7444. (pdf)

36.“Formation of Hydrindanes and Tricyclo[,8]nonanes via 6-Endo Trapping of the Nazarov Oxyallyl Intermediate,” Cindy C. Browder and F. G. West, Synlett 1999, 1363-1366.

35.“Chirality Transfer from Carbon to Nitrogen to Carbon via Cyclic Ammonium Ylides,” Kevin W. Glaeske, Atta M. Arif and F. G. West, Organic Letters 1999, 31-33. (pdf)

34.“A Novel Cycloisomerization of Tetraenones:  4+3 Trapping of the Nazarov Oxyallyl Intermediate,” Yong Wang, Atta M. Arif and F. G. West, J. Am. Chem. Soc. 1999, 121, 876-877. (pdf)

33.“Synthesis of Bridged Bicyclic Ethers and Fused Oxetanes from Pyran-4-ones via Tandem Solvent Trapping and Norrish Type II Cyclization,” Mike Fleming, Rehan Basta, Peter V. Fisher, Scott Mitchell and F. G. West, J. Org. Chem. 1999, 64, 1626-1629. (pdf)


32.“The Reductive Nazarov Cyclization,” Sören Giese and F. G. West, Tetrahedron Lett. 1998, 39, 8393-8996. (pdf)

31.“Medium Ring Ethers via [1,2]-Shift of Acetal-Derived Oxonium Ylides,” Richland W. Tester and F. G. West, Tetrahedron Lett. 1998, 39, 4631-4634. (pdf)

30.“Medium Sized Carbocycles and Ethers from 4-Pyrones:  A Photocyclization-Fragmentation Approach,” Clare M. Amann, P. V. Fisher, Mark L. Pugh and F. G. West, J. Org. Chem. 1998, 63, 2806-2807. (pdf)

29.“Highly Diastereoselective Cycloisomerization of Acyclic Trienones.  The Interrupted Nazarov Reaction,” John A. Bender, Alan E. Blize, Cindy C. Browder, Sören Giese and F. G. West, J. Org. Chem.1998, 63, 2430-2431. (pdf)

28.“1,3-Dioxolan-2-ylium Cations from Acylfurans:  Conversion of Furyl Ketones to Esters Under Nonoxidative Conditions,” John A. Bender, Samantha Daves and F. G. West, Tetrahedron Lett. 1998, 39, 2051-2054. (pdf)


27.“A Short, Enantioselective Synthesis of (-)-Epilupinine from Proline via a Spirocyclic Ammonium Ylide,” B. N. Naidu and F. G. West, Tetrahedron 1997, 53, 16565-16574. (pdf)

26.“Sonolysis Promotes Indirect C-Co Bond Cleavage of Alkylcob(III)alamin,” W. Allen Howard, Jr., Ashraf Bayomi, Ettaya Natarajan, Mohsen A. Aziza, Omar El-Ahmady, Charles B. Grissom and Frederick G. West, Bioconj. Chem. 1997, 8, 498-502. (pdf)

25.“Tandem Enamine Michael Additions to 4-Mesyloxycyclopentenones:  Bridged Tricyclic Skeletons via a Net 3+2 Construction,” G. U. Gunawardena, Atta M. Arif and F. G. West, J. Am. Chem. Soc. 1997, 119, 2066-2067. (pdf)


24.“Efficient Construction of Bi- and Tricyclic Cyclooctanoid Systems via Crossed [4+4]-Photocycloadditions of Pyran-2-ones,”  Charles E. Chase, John A. Bender and F. G. West, Synlett,1996, 1173.

23.“The Total Synthesis of a Natural Cardenolide:  (+)-Digitoxigenin,” Gilbert Stork, Fred West, Hee Yoon Lee, Richard C. A. Isaacs and Shino Manabe, J. Am. Chem. Soc. 1996, 118, 10660. (pdf)


22.“Unexpected and Efficient Photochemical Rearrangement of 6-Hydroxyethylpyran-2-ones to 4-Alkylidene-5,6-dihydropyrans,” Charles E. Chase, Michael B. Jarstfer, Atta M. Arif and F. G. West, Tetrahedron Lett. 1995, 36, 8531. (pdf)

21.“Unprecedented Diastereoselective Addition Reactions of 6,6-Dimethylcyclo- hexadienyl  Titanium Complexes  to  Aldehydes  and  Ketones,” Anne  M. Wilson,  F. G.  West,  Atta M.  Arif  and  Richard D.  Ernst,  J. Am. Chem. Soc. 1995, 117, 8490. (pdf)


20.“Intramolecular Carboxylic Acid Trapping of Pyran-4-one Derived Zwitterions:  A Novel Synthesis of Fused Bicyclic Lactones,” F. G. West, C. M. Amann and P. V. Fisher, Tetrahedron Lett. 1994, 35, 9653. (pdf)

19.“Profound Catalyst Effects in the Generation and Reactivity of Carbenoid-Derived Cyclic Ylides,” F. G. West, B. N. Naidu and Richland W. Tester, J. Org. Chem. 1994, 59, 6892. (pdf)

18.“A Concise, Stereospecific Synthesis of Epilupinine via [1,2]-Shift of a Proline-Derived Ammonium Ylide,” F. G. West and B. N. Naidu, J. Am. Chem. Soc. 1994, 116, 8420. (pdf)

17.“Applications of Stevens [1,2]-Shifts of Cyclic Ammonium Ylides.  A Route to Morpholin-2-ones,” F. G. West and B. N. Naidu, J. Org. Chem. 1994, 59, 6051. (pdf)


16.“O-Bridged  Medium  Sized  Rings  Via  Bicyclic  Oxonium  Ylides,”  F.  G. West, T. H. Eberlein and Richland W. Tester, J. Chem. Soc., Perkin Trans. 1, 1993, 2857. (pdf)

15.“Intramolecular [4+3]-Cycloadditions of Photochemically Generated Oxyallyl Zwitterions:  A Route to Functionalized Cyclooctanoid Skeletons,” F. G. West, C. Hartke-Karger, Daniel J. Koch, Cynthia E. Kuehn and Atta M. Arif J. Org. Chem. 1993, 58, 6795. (pdf)

14.“Novel Bicyclic Oxazolines Via Nitrile Capture of Photochemically Generated Oxyallyl Zwitterions,” F. G. West and Daniel J. Koch, J. Chem. Soc., Chem. Commun. 1993, 1681.

13.“Pseudo-cine Substitution via Internal Delivery. Formal Cyclopentadienone-Ketone Michael  Adducts,” F. G. West and G. U. Gunawardena, J. Org. Chem. 1993, 58, 5043. (pdf)

12.“Photochemical Ring-Contraction of Fused Bicyclic 4-Pyrones:  A Novel 2-Step Cyclopentannulation Approach,” F. G. West, P. V. Fisher, G. U. Gunawardena and Scott Mitchell, Tetrahedron Lett. 1993, 34, 4583. (pdf)

11.“Intramolecular Arene Trapping of Pyran-4-one Derived Zwitterions:  A Two-Step Synthesis of Tetrahydrobenz[e]inden-1-ones,” F. G. West and Duke W. Willoughby, J. Org. Chem. 1993, 58, 3796. (pdf)

10.“Intramolecular Photochemical [4+4]-Cycloadditions of 2-Pyrones: An Efficient Approach to Substituted Cyclooctanoids,” F. G. West, C. E. Chase and A. M. Arif, J. Org. Chem. 1993, 58, 3794. (pdf)

9.“One-Step Synthesis of Tertiary a-Aminoketones and a-Amino Esters From Amines and Diazocarbonyl Compounds,” F. G. West, Kevin Glaeske and B. N. Naidu, Synthesis, 1993, 977.

8.“Pseudo-cine Rearrangements of 4-Mesyloxy-2-cyclopentenones: An Efficient Route to 2,4-Disubstituted-2-Cyclopentenones,”  F. G. West and Gamini U. Gunawardena, J. Org. Chem. 1993, 58, 2402. (pdf)

7.“Intramolecular Alkene Trapping of Pyran-4-one Derived Zwitterions: A Novel Synthesis of Diquinanes and Hydrindans,” F. G. West, Peter V. Fisher and A. M. Arif, J. Am. Chem. Soc. 1993, 115, 1595. (pdf)

6.“New Route to Substituted Piperidines via the Stevens [1,2]-Shift of Ammonium Ylides,” F. G. West and B. N. Naidu, J. Am. Chem. Soc. 1993, 115, 1177. (pdf)


5.“The Stevens [1,2]-Shift of Oxonium Ylides:  A Route to Substituted Tetrahydrofuranones,” T. H. Eberlein, F. G. West and R. W. Tester, J. Org. Chem. 1992, 57, 3479. (pdf)


4.“The Photochemistry of Pyran-4-ones:  Intramolecular Trapping of the Zwitterionic Intermediate with Pendant Hydroxyl Groups,” F. G. West, Peter V. Fisher and C. A. Willoughby J. Org. Chem. 1990, 55, 5936. (pdf)


3.“Nonstabilized Imidate Ylides by the Desilylation Method:  A Route to the Pyrrolizidine Alkaloids Retronecine and Indicine,” E. Vedejs, S. Larsen and F. G. West, J. Org. Chem. 1985, 50, 2170.(pdf)


2.“Thioimidate Methylides by the Desilylation Method:  An Improved Synthesis of Pyrrolines and Pyrroles,” E. Vedejs and F. G. West, J. Org. Chem. 1983, 48, 4773. (pdf)


1.“A Method for Quantitative Amino Acid Analysis Using Precolumn o-Phthalaldehyde Derivatization and High Performance Liquid Chromatography,” Brent R. Larsen and Frederick G. West, J. Chromat. Sci.1981, 19, 259.

Reviews and Book Chapters

16. F. G. West, O. Scadeng, Y.-K. Wu, R. J. Fradette and S. Joy, In Comprehensive Organic Synthesis, 2nd Edition, G. A. Molander, P. Knochel, Eds.; Vol. 5, Elsevier: Oxford, 2014; pp. 827–866.

15.“Intramolecular generation and rearrangement of oxonium ylides: methodology studies and their application in synthesis,” Graham K. Murphy, Craig Stewart, F.G. West, Tetrahedron, 2013, 69, 2667-2686

14.”Preparation and Synthetic Applications of Azetidines,”Bott, T. M.; West F. G. Heterocycles 2012, 84, 223-264. 

13.“Advances in the Nazarov Cyclization,” Nakanishi, W.; West F. G. Curr. Opin. Drug Discov. 2009, 12, 732-751.

12.“Interrupting the Nazarov reaction: domino and cascade processes utilizing cyclopentenyl cations,” Tina N. Grant, Curtis J. Rieder, F. G. West, Chem. Commun. 2009, 5676-5688. (pdf)

11.“Survey of Chemical Syntheses of the Pyrrolizidine Alkaloids Turneforcidine and Platynecine,” John A. Vanecko and F. G. West, Heterocycles 2007, 74, 125–143.

10.“The Stevens [1,2]-Shift of Ammonium Ylides:  Recent Synthetic Applications,” John A. Vanecko, Hayley Wan and F. G. West, Tetrahedron 2006, 62, 1043–1062. (pdf)

9.Invited review of Science of Synthesis, Volume 27:  Carbon with Two Carbon-Heteroatom Bonds:  Heteroatom Analogues of Aldehydes and Ketones; Padwa, A., Ed.; 2004; In Synthesis 2005. 508

8.“Rearrangement Processes of Oxonium and Ammonium Ylides Formed by Rhodium-Catalyzed Carbene-Transfer,” F. G. West In Recent Advances in Rhodium-Catalyzed Organic Reactions; P. A. Evans, Ed.; Wiley:  New York, 2004.

7.“Photochemical Rearrangement and Trapping Reactions of 4-Pyrones,” F. G. West In CRC Handbook of Photochemistry and Photobiology, W. A. Horspool, Ed.; CRC Press:  Boca Raton, FL, in press.

6.“New Efficient Iterative Approaches to Polycyclic Ethers,” Fredrik P. Marmsäter and F. G. West, Chem. Eur. J. 2002, 8, 4346-4353. (pdf)

5.“Generation of Ammonium Ylides from Metal Carbenoids,” J. S. Clark and F. G. West In Nitrogen, Oxygen and Sulfur Ylides in Synthesis:  A Practical Approach, J. S. Clark, Ed.; Oxford University Press:  Oxford, 2002, 115-134.

4.“Diagnostic and Therapeutic Analogues of Cobalamin,” H. P. C. Hogenkamp, Douglas A. Collins, Charles B. Grissom and Frederick G. West In Chemistry and Biochemistry of B12;R. Bannerjee, Ed.; Wiley:  New York, 1999, 385-410.

3.“The Photochemistry of Dienes and Polyenes:  Application to the Synthesis of Complex Molecules,” John M. Nuss and Frederick G. West In The Chemistry of Dienes and Polyenes; Z. Rappoport, Ed.; John Wiley:  Chichester, 1997, pp. 263-324.

2.“Photocyclization and Photocycloaddition Reactions of 4- and 2-Pyrones,” F. G. West In Advances in Cycloaddition, M. Lautens, Ed.; JAI Press:  Greenwich, CT, Vol. 4, 1997, pp. 1-40.

1.“Ylides by Desilylation of Trimethylsilylmethylonium Salts,” E. Vedejs and F. G. West, Chemical Reviews1986, 86, 941. (pdf)

Other Invited Chapters

5.“Targeting Leukemia Cells with Cobalamin Bioconjugates,” Alice M. Mitchell, Ashraf Bayomi, Ettaya Natarajan, Louis R. Barrows, Frederick G. West and Charles B. Grissom, In Enzyme Mechanisms:  Proceedings of the 26th Steenbock Symposium, P. Frey, D. Northrop, Eds.; IOS Press:  Amsterdam, 1999, 150-154.

4.“Lithium Hydroperoxide” Frederick G. West and John A. Bender In Encyclopedia of Reagents for Organic Synthesis, L. Paquette, Ed.; John Wiley:  New York, 1995, vol. 5, pp 3130-3132.

3.t-Butyl Chloromethyl Ether” F. G. West and John A. Bender In Encylcopedia of Reagents for Organic Synthesis, L. Paquette, Ed.; John Wiley:  New York, 1995, vol. 2, p 861.

2.“Bromine-Silver(I) Oxide” F. G. West and John A. Bender In Encyclopedia of Reagents for Organic Synthesis, L. Paquette, Ed.; John Wiley:  New York, 1995, vol. 1, pp 688-689.

1.“N,O-Bis(trifluoroacetyl)hydroxylamine” F. G. West and John A. Bender In Encyclopedia of Reagents for Organic Synthesis, L. Paquette, Ed.; John Wiley:  New York, 1995, vol. 1, pp 582-583.